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1

Chiral biomimetic NADH models in the benzo[b]-1,6-naphthyridine series. A novel class of stable, reactive and highly enantioselective NADH mimics

Jean-Luc Vasse, Vincent Levacher, Jean Bourguignon, Georges Dupas

Journal:

Year:

2003

Language:

english

File:

PDF, 317 KB

english, 2003

2

Chemoselective, accelerated and stereoselective aza-Michael addition of amines to N-phenylmaleimide by using TMEDA based receptors

Yuefeng Bi, Laëtitia Bailly, Francis Marsais, Vincent Levacher, Cyril Papamicaël, Georges Dupas

Journal:

Tetrahedron: Asymmetry

Year:

2004

Language:

english

File:

PDF, 296 KB

english, 2004

3

Palladium-Catalyzed Carbonylation of (Hetero)Aryl, Alkenyl and Allyl Halides by Means of N- Hydroxysuccinimidyl Formate as CO Surrogate

Barré, Anaïs, Ţînţaş, Mihaela-Liliana, Alix, Florent, Gembus, Vincent, Papamicaël, Cyril, Levacher, Vincent

Journal:

Journal of Organic Chemistry

Year:

2015

Language:

english

File:

PDF, 7.95 MB

english, 2015

4

Rational design of carbamate-based dual binding site and central AChE inhibitors by a “biooxidisable” prodrug approach: Synthesis, in vitro evaluation and docking studies

Ţînţaş, Mihaela-Liliana, Gembus, Vincent, Alix, Florent, Barré, Anaïs, Coadou, Gaël, Truong, Lina, Sebban, Muriel, Papamicaël, Cyril, Oulyadi, Hassan, Levacher, Vincent

Journal:

European Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 1022 KB

english, 2018

5

Polymer-Bound Pyridine-Bis(oxazoline). Preparation through Click Chemistry and Evaluation in Asymmetric Catalysis

Mélanie Tilliet, Stina Lundgren, Christina Moberg, Vincent Levacher

Journal:

Advanced Synthesis & Catalysis

Year:

2007

Language:

english

File:

PDF, 138 KB

english, 2007

6

Organocatalytic Enantioselective Protonation of Silyl Enolates Mediated by Cinchona Alkaloids and a Latent Source of HF

Thomas Poisson, Vincent Dalla, Francis Marsais, Georges Dupas, Sylvain Oudeyer, Vincent Levacher

Journal:

Angewandte Chemie

Year:

2007

Language:

english

File:

PDF, 107 KB

english, 2007

7

Enantioselective Phase-Transfer Catalysis: Synthesis of Pyrazolines

Olivier Mahé, Dr. Isabelle Dez, Dr. Vincent Levacher, Dr. Jean-François Brière

Journal:

Angewandte Chemie

Year:

2010

Language:

english

File:

PDF, 332 KB

english, 2010

8

Organocatalytic Enantioselective Protonation of Silyl Enolates Mediated by Cinchona Alkaloids and a Latent Source of HF

Thomas Poisson, Vincent Dalla, Francis Marsais, Georges Dupas, Sylvain Oudeyer, Vincent Levacher

Journal:

Angewandte Chemie International Edition

Year:

2007

Language:

english

File:

PDF, 108 KB

english, 2007

9

Enantioselective Phase-Transfer Catalysis: Synthesis of Pyrazolines

Olivier Mahé, Dr. Isabelle Dez, Dr. Vincent Levacher, Dr. Jean-François Brière

Journal:

Angewandte Chemie International Edition

Year:

2010

Language:

english

File:

PDF, 351 KB

english, 2010

10

ChemInform Abstract: Diastereoselective Protonation of Lactam Enolates Derived from (R)-Phenylglycinol. A Novel Asymmetric Route to 4-Phenyl-1,2,3,4-tetrahydroisoquinolines.

Nicolas Philippe, Vincent Levacher, Georges Dupas, Guy Queguiner, Jean Bourguignon

Journal:

Year:

2000

File:

PDF, 29 KB

2000

11

ChemInform Abstract: Synthesis of N-Methyl-4-pyridyl-1,2,3,4-tetrahydroisoquinolines via a Pictet—Spengler Cyclization.

Laurence Prat, Ronan Bureau, Cyril Daveu, Vincent Levacher, Georges Dupas, Guy Queguiner, Jean Bourguignon

Journal:

Year:

2001

File:

PDF, 29 KB

2001

12

ChemInform Abstract: Synthesis of a Heterocyclic Receptor for Carboxylic Acids.

Gregory Moore, Vincent Levacher, Jean Bourguignon, Georges Dupas

Journal:

Year:

2001

File:

PDF, 29 KB

2001

13

Atropoisomeric Quinolinium Salt Promoting the Access to Both Enantiomeric Forms of Methyl Mandelate: A Versatile NADH Mimic.

Jean-Luc Vasse, Vincent Levacher, Jean Bourguignon, Georges Dupas

Journal:

Year:

2003

File:

PDF, 99 KB

2003

14

Highly Stereoselective Friedel—Crafts Type Cyclization. Facile Access to Enantiopure 1,4-Dihydro-4-phenyl Isoquinolinones.

Nicolas Philippe, Francois Denivet, Jean-Luc Vasse, Jana Sopkova-de Olivera Santos, Vincent Levacher, Georges Dupas

Journal:

Year:

2004

File:

PDF, 153 KB

2004

15

Novel Extension of Meyers′ Methodology: Stereoselective Construction of Axially Chiral 7,5-Fused Bicyclic Lactams.

Mael Penhoat, Vincent Levacher, Georges Dupas

Journal:

Year:

2004

File:

PDF, 139 KB

2004

16

ortho-Lithiation of S-tert-Butyl-S-phenylsulfoximines. New Route to Enantiopure Sulfinamides via a De-tert-Butylation Reaction.

Stephane Gaillard, Cyril Papamicael, Georges Dupas, Francis Marsais, Vincent Levacher

Journal:

Year:

2005

File:

PDF, 37 KB

2005

17

Single-Step Preparation of a 4-(Dimethylamino)pyridine Analogue Bearing a Sulfoxide as New Chiral Inducer. Preliminary Evaluation as Nucleophilic Catalyst.

Thomas Poisson, Mael Penhoat, Cyril Papamicael, Georges Dupas, Vincent Dalla, Francis Marsais, Vincent Levacher

Journal:

Year:

2006

File:

PDF, 15 KB

2006

18

ChemInform Abstract: Product-Catalyzed Addition of Alkyl Nitriles to Unactivated Imines Promoted by Sodium Aryloxide/Ethyl(trimethylsilyl)acetate (ETSA) Combination.

Thomas Poisson, Vincent Gembus, Sylvain Oudeyer, Francis Marsais, Vincent Levacher

Journal:

Year:

2009

File:

PDF, 45 KB

2009

19

ChemInform Abstract: Preparation of β-Lactams by Mannich-Type Addition of Ethyl(trimethylsilyl)acetate (ETSA) to N-(2-Hydroxyphenyl)aldimine Sodium Salts.

Vincent Gembus, Thomas Poisson, Sylvain Oudeyer, Francis Marsais, Vincent Levacher

Journal:

Year:

2010

File:

PDF, 31 KB

2010

20

ChemInform Abstract: TBD-Organocatalyzed Synthesis of Pyrazolines.

Olivier Mahe, Denis Frath, Isabelle Dez, Francis Marsais, Vincent Levacher, Jean-Francois Briere

Journal:

Year:

2010

File:

PDF, 33 KB

2010

21

ChemInform Abstract: Novel Approach for the Synthesis of Five-Membered-Ring-Fused Pyrazinones.

Vincent Gembus, Solenn Janvier, Jean-Pierre Lecouve, Philippe Gloanec, Francis Marsais, Vincent Levacher

Journal:

Year:

2010

File:

PDF, 31 KB

2010

22

ChemInform Abstract: Synthesis of Pyrazolines by a Site Isolated Resin-Bound Reagents Methodology.

Vincent Gembus, Jean-Jacques Bonnet, Francois Janin, Pierre Bohn, Vincent Levacher, Jean-Francois Briere

Journal:

Year:

2010

File:

PDF, 39 KB

2010

23

ChemInform Abstract: Enantioselective Phase-Transfer Catalysis: Synthesis of Pyrazolines.

Olivier Mahe, Isabelle Dez, Vincent Levacher, Jean-Francois Briere

Journal:

Year:

2011

File:

PDF, 35 KB

2011

24

ChemInform Abstract: Organocatalyzed Enantioselective Protonation of Silyl Enol Ethers: Scope, Limitations, and Application to the Preparation of Enantioenriched Homoisoflavones.

Thomas Poisson, Vincent Gembus, Vincent Dalla, Sylvain Oudeyer, Vincent Levacher

Journal:

Year:

2011

File:

PDF, 64 KB

2011

25

ChemInform Abstract: Highly Regio- and Diastereoselective Anionic [3 + 2] Cycloaddition under Phase Transfer Catalytic Conditions.

Vincent Gembus, Svetlana Postikova, Vincent Levacher, Jean-Francois Briere

Journal:

Year:

2011

File:

PDF, 36 KB

2011

26

ChemInform Abstract: Catalytic Enantioselective Protonation of Enol Trifluoroacetates by Means of Hydrogenocarbonates and Cinchona Alkaloids.

Aurelie Claraz, Jerome Leroy, Sylvain Oudeyer, Vincent Levacher

Journal:

Year:

2011

File:

PDF, 33 KB

2011

27

Novel Approach for the Synthesis of Five-Membered-Ring-Fused Pyrazinones

Vincent Gembus, Solenn Janvier, Jean-Pierre Lecouvé, Philippe Gloanec, Francis Marsais, Vincent Levacher

Journal:

European Journal of Organic Chemistry

Year:

2010

Language:

english

File:

PDF, 114 KB

english, 2010

28

Synthesis of N-methyl-4-pyridyl-1,2,3,4-tetrahydroisoquinolines via a pictet-spengler cyclisation

Laurence Prat, Vincent Levacher, Georges Dupas, Guy Quéguiner, Jean Bourguignon, Ronan Bureau, Cyril Daveu

Journal:

Journal of Heterocyclic Chemistry

Year:

2000

File:

PDF, 345 KB

2000

29

Bromine-Lithium exchange on bromo-8-hydroxyquinolines via formation of their sodium salts

Florence Mongin, Jean-Marie Fourquez, Stéphanie Rault, Vincent Levacher, Alain Godard, François Trécourt, Guy Quéguiner

Journal:

Tetrahedron Letters

Year:

1995

Language:

english

File:

PDF, 274 KB

english, 1995

30

Efficient preparation of polymer-supported enantiopure chiral aminoalcohols via phenolic spacers

Vincent Levacher, Christina Moberg

Journal:

Reactive Polymers

Year:

1995

Language:

english

File:

PDF, 830 KB

english, 1995

31

Chiral ditopic receptors. Application to palladium-catalyzed allylic alkylation

Jean Bourguignon, Ulf Bremberg, Georges Dupas, Kristina Hallman, Lars Hagberg, Laurent Hortala, Vincent Levacher, Serghey Lutsenko, Emmanuel Macedo, Christina Moberg, Guy Quéguiner, Fredrik Rahm

Journal:

Year:

2003

Language:

english

File:

PDF, 255 KB

english, 2003

32

Synthesis and study of a heterocyclic receptor designed for carboxylic acids

Gregory Moore, Cyril Papamicaël, Vincent Levacher, Jean Bourguignon, Georges Dupas

Journal:

Year:

2004

Language:

english

File:

PDF, 510 KB

english, 2004

33

ortho-Lithiation of S-tert-butyl-S-phenylsulfoximines. New route to enantiopure sulfinamides via a de-tert-butylation reaction

Stéphane Gaillard, Cyril Papamicaël, Georges Dupas, Francis Marsais, Vincent Levacher

Journal:

Year:

2005

Language:

english

File:

PDF, 428 KB

english, 2005

34

Convenient preparation of bifunctional pybox ligands

Mélanie Tilliet, Anders Frölander, Vincent Levacher, Christina Moberg

Journal:

Year:

2008

Language:

english

File:

PDF, 328 KB

english, 2008

35

Preparation of axially chiral quinolinium salts related to NAD+ models: new investigations of these biomimetic models as ‘chiral amide-transferring agents’

Stéphane Leleu, Cyril Papamicaël, Francis Marsais, Georges Dupas, Vincent Levacher

Journal:

Tetrahedron: Asymmetry

Year:

2004

Language:

english

File:

PDF, 389 KB

english, 2004

36

New development of Meyers’ methodology: stereoselective preparation of an axially chiral 5,7-fused bicyclic lactam related to circumdatins/benzomalvins and asperlicins

Maël Penhoat, Pierre Bohn, Georges Dupas, Cyril Papamicaël, Francis Marsais, Vincent Levacher

Journal:

Tetrahedron: Asymmetry

Year:

2006

Language:

english

File:

PDF, 161 KB

english, 2006

37

New advances in stereoselective Meyers’ lactamization. Application to the diastereoselective synthesis of β-substituted oxazoloazepinones

Alexis Bouet, Sylvain Oudeyer, Georges Dupas, Francis Marsais, Vincent Levacher

Journal:

Tetrahedron: Asymmetry

Year:

2008

Language:

english

File:

PDF, 463 KB

english, 2008

38

Meyers’ bicyclic lactam formation under mild and highly stereoselective conditions

Maël Penhoat, Stephane Leleu, Georges Dupas, Cyril Papamicaël, Francis Marsais, Vincent Levacher

Journal:

Tetrahedron Letters

Year:

2005

Language:

english

File:

PDF, 147 KB

english, 2005

39

Stable annelated chiral NADH models with a rigidified amide part in the quinoline series: synthesis, reactivity and grafting on a Merrifield resin

Christiane Vitry, Jean-Luc Vasse, Georges Dupas, Vincent Levacher, Guy Quéguiner, Jean Bourguignon

Journal:

Year:

2001

Language:

english

File:

PDF, 267 KB

english, 2001

40

Chiral NADH models with restricted or blocked rotation at the amide function: attempts to interpret the mechanism of the enantioselective hydrogen transfer to methyl benzoylformate

Christiane Vitry, Joelle Bédat, Yann Prigent, Vincent Levacher, Georges Dupas, Isabelle Salliot, Guy Quéguiner, Jean Bourguignon

Journal:

Year:

2001

Language:

english

File:

PDF, 221 KB

english, 2001

41

Synthesis of annelated NADH models in Benzothieno[2,3-b]pyridine and Pyridol[2,3-b]indole Series

Vincent Levacher, Nadjib Boussad, Georges Dupas, Jean Bourguignon, Guy Quéguiner

Journal:

Year:

1992

Language:

english

File:

PDF, 739 KB

english, 1992

42

Highly stereoselective Friedel–Crafts type cyclization. Facile access to enantiopure 1,4-dihydro-4-phenyl isoquinolinones

Nicolas Philippe, François Denivet, Jean-Luc Vasse, Jana Sopkova-de Olivera Santos, Vincent Levacher, Georges Dupas

Journal:

Year:

2003

Language:

english

File:

PDF, 311 KB

english, 2003

43

Synthesis of a heterocyclic receptor for carboxylic acids

Gregory Moore, Vincent Levacher, Jean Bourguignon, Georges Dupas

Journal:

Tetrahedron Letters

Year:

2001

Language:

english

File:

PDF, 95 KB

english, 2001

44

Study of the Reduction of Enamides with an NADH Model

Corine Leroy, Vincent Levacher, Georges Dupas, Jean Bourguignon, Guy Quéguiner

Journal:

Tetrahedron Letters

Year:

1992

Language:

english

File:

PDF, 250 KB

english, 1992

45

New NADH models bearing a phosphonate or a chiral oxazaphospholidine oxide at the dihydropyridine ring

Jean-Luc Vasse, Sophie Goumain, Vincent Levacher, Georges Dupas, Guy Quéguiner, Jean Bourguignon

Journal:

Tetrahedron Letters

Year:

2001

Language:

english

File:

PDF, 71 KB

english, 2001

46

Rational design of novel axially chiral NADH models based on configurational control of atropisomeric lactams

Jean-Luc Vasse, Georges Dupas, Jack Duflos, Guy Quéguiner, Jean Bourguignon, Vincent Levacher

Journal:

Tetrahedron Letters

Year:

2001

Language:

english

File:

PDF, 98 KB

english, 2001

47

Deracemization of alkyl diarylmethanes using (−)-sparteine or a chiral proton source

Laurence Prat, Georges Dupas, Jack Duflos, Guy Quéguiner, Jean Bourguignon, Vincent Levacher

Journal:

Tetrahedron Letters

Year:

2001

Language:

english

File:

PDF, 79 KB

english, 2001

48

Design of new axially chiral NADH mimics. Mechanistic investigation of the enantioselective hydride transfer

Jean-Luc Vasse, Georges Dupas, Jack Duflos, Guy Quéguiner, Jean Bourguignon, Vincent Levacher

Journal:

Tetrahedron Letters

Year:

2001

Language:

english

File:

PDF, 139 KB

english, 2001

49

Acyl transfer of 8-acetoxy-2-oxazolinylquinoline assisted by hydrogen bonding formation

Laurent Hortala, Christina Moberg, Vincent Levacher, Jean Bourguignon, Georges Dupas

Journal:

Tetrahedron Letters

Year:

2002

Language:

english

File:

PDF, 174 KB

english, 2002

50

An efficient synthesis of 3-cyanoquinoline derivatives

Patricia Charpentier, Virginie Lobrégat, Vincent Levacher, Georges Dupas, Guy Quéguiner, Jean Bourguignon

Journal:

Tetrahedron Letters

Year:

1998

Language:

english

File:

PDF, 246 KB

english, 1998

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